Oxford OPP were on the scene of a fatal collision north of Delhi on Tuesday evening.
A collision between a pickup truck and SUV shuttered the intersection of Base Line and New Road for several hours.
The 28-year-old resident of Port Colborne, and driver of the SUV was pronounced dead at the scene. Three other occupants of the SUV were transported to hospital with non-life-threatening injuries.
The lone pickup truck occupant was also transported to hospital with non-life-threatening injuries.
Anyone with information including dashcam footage is asked to contact police.